Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin

Catalog number ICH1124-50mg

Price for ICH1124-50mg

Size / count 50 mg

Specifications

Catalog number: ICH1124-50mg
Size / count: 50 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-alpha proteins and a single IFN-beta protein. The second class, type II IFN, consists of a single protein, IFN-gamma. IFN-alpha and IFN-beta signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN-beta has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-beta’s therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.
CAS Number: 9007-83-4
Specifications: Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) recognizes Mouse IFN beta
Product Name Alternative: IFN-b, IFN-beta, Type-1 interferon, Interferon beta
UniProt: P01575
Host: Armenian Hamster
Species Reactivity: Mouse
Target: IFN beta
Isotype: IgG
Clone: MIB-5E9.1
Applications: Western Blot, Blocking
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Anti-IFN beta In Vivo Antibody - Low Endotoxin (MIB-5E9.1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Fibroblasts & epithelial cells
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Armenian-Hamster-IgG-Isotype-Control-for-In-Vivo-Low-Endotoxin-PIP-ICH2251

Frequently Asked Questions

What is the catalog number for Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin is ICH1124-50mg.

What sizes are available for Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin?

Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin is available in the following size(s): 50 mg.

Is Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse IFN Beta (MIB-5E9.1) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.