Bulk Anti-Human Hepsin (2D5-1.9) Antibody

Catalog number ICH1160-5mg

Price for ICH1160-5mg

Size / count 5 mg

Specifications

Catalog number: ICH1160-5mg
Size / count: 5 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Hepsin is a type II transmembrane serine protease (TTSP) expressed on the surface of epithelial cells including the liver, kidney, prostate, and thyroid in human tissues. The physiological function of hepsin is unclear, although, In vitro studies have shown that hepsin activates blood clotting factors VII, XII, and IX, pro-urokinase (pro-uPA), and pro-hepatocyte growth factor (pro-HGF). The over-expression of hepsin has been implicated in several types of cancer, especially ovarian and prostate, which makes it an attractive diagnostic marker for cancers. Most notably, hepsin has been identified as one of the most highly induced genes in prostate cancer, and this over-expression is correlated with the cancer progression and metastasis. Furthermore anti-hepsin antibodies have been shown to inhibit the invasion of human prostate cancer cells.1
CAS Number: 9007-83-4
Specifications: Clone 2D5 recognizes Human hepsin. It binds to a separate epitope than clone 3H10.1. These clones do not interfere with one another.
Product Name Alternative: Serine protease hepsin, hpn
UniProt: P05981
Host: Mouse
Species Reactivity: Human
Target: Hepsin
Isotype: IgG2a Kappa
Clone: 2D5-1.9
Applications: ELISA, FC, WB
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
Antigen Distribution: Hepsin is expressed on the surface of epithelial cells including the liver, kidney, prostate, and thyroid in human tissues.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Mouse-IgG2a-In-Vivo-Isotype-Control-Low-Endotoxin-C1.18.4-ICH2245

Frequently Asked Questions

What is the catalog number for Bulk Anti-Human Hepsin (2D5-1.9) Antibody?

The catalog number for Bulk Anti-Human Hepsin (2D5-1.9) Antibody is ICH1160-5mg.

What sizes are available for Bulk Anti-Human Hepsin (2D5-1.9) Antibody?

Bulk Anti-Human Hepsin (2D5-1.9) Antibody is available in the following size(s): 5 mg.

Is Bulk Anti-Human Hepsin (2D5-1.9) Antibody in stock?

Bulk Anti-Human Hepsin (2D5-1.9) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.