Anti-Mouse CD370 (1F6) In Vivo Antibody - Low Endotoxin

Specifications

Catalog number

ICH1168-100mg

Size / count

100 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CLEC9A, also known as DNGR1 is defined as a type II membrane protein with a single extracellular C-type lectin domain¹. CLEC9A is involved with adaptive immune response during infection. Additionally, CLEC9A, is being investigated for potential to enhance immune responses produced by vaccines.

CAS Number

9007-83-4

Specifications

Clone 1F6 recognizes an epitope on mouse DNGR1

Product Name Alternative

CD370, DNGR-1, C-Type Lectin Domain Family 9 Member A

UniProt

Q8BRU4

Host

Rat

Species Reactivity

Mouse

Target

CLEC9A

Isotype

IgG1

Clone

1F6

Applications

Flow Cytometry, Immunofluorescence, Western Blot

Purification Method

This monoclonal antibody was purified using Protein G

Concentration

>2.0 mg/mL

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Formulation

This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free

Antigen Distribution

CD370 (CLEC9A) in mice is expressed on CD8+ DCs and at low levels by plasmacytoid DCs.

Aggregation

Aggregation level ≤ 5%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

https://www.ichor.bio/product/Rat-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-GL113-ICH2246