- Catalog number
- ICH1177-5mg
- Size / count
- 5 mg
- Dry ice
- No
- Hazardous
- No
- Discontinued
- No
- Background
- CD1d antibody, D5, recognizes human CD1d, also known as CD1.1 and Ly-38, a 48 kDa type 1 membrane glycoprotein that belongs to the cluster of differentiation 1 (CD1) family of glycoproteins. CD1d is expressed on epithelial cells and monocyte-derived antigen presenting cells (APCs), including monocytes, DCs, and macrophages. CD1d is an MHC class I-like molecule involved in the presentation of lipid antigens, such as α-galactosylceramide (α-GalCer), to a highly conserved T cell subset, named invariant natural killer T (iNKT) cells or CD1d-restricted T cells1. Following activation, iNKT cells rapidly proliferate and produce large amounts of cytokines and cytolytic mediators
- CAS Number
- 9007-83-4
- Specifications
- Clone D5 recognizes an epitope on human CD1d
- Product Name Alternative
- R3G1
- UniProt
- P15813
- Host
- Mouse
- Species Reactivity
- Human
- Target
- CD1d
- Isotype
- IgG2b
- Clone
- D5
- Applications
- Immunoprecipitation, Western Blot
- Purification Method
- This monoclonal antibody was purified using Protein A
- Concentration
- ≥ 5.0 mg/mL
- Endotoxin
- <1.0 EU/mg as determined by the LAL method
- Purity
- ≥95% monomer by analytical SEC, >95% by SDS Page
- Buffer
- ICH3001-100mL
ICH3002-100mL
ICH3003-100mL
- Shipping Conditions
- Blue ice
- Storage Conditions
- This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Formulation
- This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
- Antigen Distribution
- CD1d is expressed on monocytes, DCs, macrophages, and epithelial cells
- Aggregation
- Aggregation level ≤ 5%
- Isotype Control
- https://www.ichor.bio/product/Mouse-IgG2b-Isotype-Control-for-In-Vivo-Low-Endotoxin-MPC-11-ICH2250