Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody

Catalog number ICH1182-25mg

Price for ICH1182-25mg

Size / count 25 mg

Specifications

Catalog number: ICH1182-25mg
Size / count: 25 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
CAS Number: 9000-83-3
Specifications: Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1
Product Name Alternative: Programmed cell death protein 1, Pdcd1, CD279
UniProt: Q02242
Host: Mouse
Species Reactivity: Mouse
Target: PD-1
Isotype: IgG2a
Clone: RMP1-14
Applications: Western Blot, Blocking, Flow Cytometry, Functional Assays
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Mouse Anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Subset of double negative thymocytes, activated T and B cells
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

What is the catalog number for Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody?

The catalog number for Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody is ICH1182-25mg.

What sizes are available for Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody?

Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody is available in the following size(s): 25 mg.

Is Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody in stock?

Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

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