Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A

Catalog number ICH1182D265A-10mg

Price for ICH1182D265A-10mg

Size / count 10 mg (2x 5 mg)

Specifications

Catalog number: ICH1182D265A-10mg
Size / count: 10 mg (2x 5 mg)
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.
CAS Number: 9000-83-3
Specifications: Mouse anti-PD-1 antibody (RMP1-14) is a recombinant antibody where the original Rat IgG2a backbone of clone RMP1-14 has been changed to Mouse IgG1. This antibody recognizes an epitope on Mouse PD-1
Product Name Alternative: Programmed cell death protein 1, Pdcd1, CD279
UniProt: Q02242
Host: CHO
Species Reactivity: Mouse
Target: PD-1
Isotype: IgG1
Clone: RMP1-14
Applications: Western Blot, Blocking, Flow Cytometry, Functional Assays
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Mouse Anti-mouse PD-1 antibody (RMP1-14) is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -70oC.
Formulation: 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Antigen Distribution: Subset of double negative thymocytes, activated T and B cells
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Mouse-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-HKSP-ICH2247

Frequently Asked Questions

What is the catalog number for Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A?

The catalog number for Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A is ICH1182D265A-10mg.

What sizes are available for Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A?

Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A is available in the following size(s): 10 mg (2x 5 mg).

Is Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A in stock?

Mouse Anti-Mouse PD-1 (RMP1-14) Recombinant Antibody D265A is currently made to order / not held in immediate stock. Contact us for lead time.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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