Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin

Catalog number ICH1196-100mg

Price for ICH1196-100mg

Size / count 100 mg

Specifications

Catalog number: ICH1196-100mg
Size / count: 100 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD134 functions as an important immune checkpoint, and its depletion in murine mouse models demonstrate that lack of CD134 expression leads to reduced CD4+ and CD8+ T cells. When CD134 is bound by its corresponding ligand (OX-40L), an optimal T cell response is generated and plays a significant role in determining the amount of memory T-cells remaining after the immune response. CD134 has also been found to play an important role in carcinogenesis, as treatment with activating in vivo antibodies against CD134 enhanced tumor growth, suggesting that CD134 is an important tumor suppressor, and its absence disrupts the immune response to tumors
CAS Number: 9007-83-4
Specifications: Clone OX-86 reacts with murine CD134 (OX-40, TNFRSF4).
Product Name Alternative: OX-40, TNFRSF4, ACT35
Host: Rat
Species Reactivity: Mouse
Target: CD134
Isotype: IgG1
Clone: OX-86
Applications: Activation, Flow Cytometry, Immunohistochemistry, Western Blotting
Purification Method: This monoclonal antibody was purified using Protein G
Concentration: ≥ 2.0 mg/mL
Endotoxin: <1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Antigen Distribution: CD134 is expressed on activated CD4 and CD8 T cells, activated regulatory T cells, B cells, NKT cells, NK cells, and neutrophils.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Rat-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-GL113-ICH2246

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin is ICH1196-100mg.

What sizes are available for Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin is available in the following size(s): 100 mg.

Is Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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