Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin

Catalog number ICH1196-25mg

Price for ICH1196-25mg

Size / count 25 mg

Specifications

Catalog number: ICH1196-25mg
Size / count: 25 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: CD134 functions as an important immune checkpoint, and its depletion in murine mouse models demonstrate that lack of CD134 expression leads to reduced CD4+ and CD8+ T cells. When CD134 is bound by its corresponding ligand (OX-40L), an optimal T cell response is generated and plays a significant role in determining the amount of memory T-cells remaining after the immune response. CD134 has also been found to play an important role in carcinogenesis, as treatment with activating in vivo antibodies against CD134 enhanced tumor growth, suggesting that CD134 is an important tumor suppressor, and its absence disrupts the immune response to tumors
CAS Number: 9007-83-4
Specifications: Clone OX-86 reacts with murine CD134 (OX-40, TNFRSF4).
Product Name Alternative: OX-40, TNFRSF4, ACT35
Host: Rat
Species Reactivity: Mouse
Target: CD134
Isotype: IgG1
Clone: OX-86
Applications: Activation, Flow Cytometry, Immunohistochemistry, Western Blotting
Purification Method: This monoclonal antibody was purified using Protein G
Concentration: ≥ 2.0 mg/mL
Endotoxin: <1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Antigen Distribution: CD134 is expressed on activated CD4 and CD8 T cells, activated regulatory T cells, B cells, NKT cells, NK cells, and neutrophils.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://www.ichor.bio/product/Rat-IgG1-Isotype-Control-for-In-Vivo-Low-Endotoxin-GL113-ICH2246

Frequently Asked Questions

What is the catalog number for Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin?

The catalog number for Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin is ICH1196-25mg.

What sizes are available for Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin?

Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin is available in the following size(s): 25 mg.

Is Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin in stock?

Anti-Mouse CD134 (OX-86) In Vivo Antibody - Low Endotoxin is currently made to order / not held in immediate stock. Contact us for lead time.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.