Anti-Rat CD71 (OX-26) In Vivo Antibody - Low Endotoxin

Specifications

Catalog number

ICH1197-100mg

Size / count

100 mg

Dry ice

No

Hazardous

No

Discontinued

No

Background

CD71 is a transferrin receptor on the cell surface that mediates the uptake of transferrin-iron complexes, thereby mediating cellular proliferation. CD71 is a homodimeric glycoprotein containing 760 amino acids and it binds to diferric transferrin. Binding by diferric transfferin causes CD71 to be internalized, and diferric iron is subsequently released. CD71 is highly expressed on malignant cells, as iron uptake is necessary for aberrant cell proliferation.

CAS Number

9007-83-4

Specifications

Clone OX-26 reacts with mouse and rat CD71 (TfR1).

Host

Mouse

Species Reactivity

Mouse, Rat

Target

CD71

Isotype

IgG2a

Clone

OX-26

Applications

Flow Cytometry,Immunohistochemistry

Purification Method

This monoclonal antibody was purified using Protein A

Concentration

≥ 2.0 mg/mL

Endotoxin

<1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE

Buffer

ICH3001-100mL ICH3002-100mL ICH3003-100mL

Shipping Conditions

Blue ice

Storage Conditions

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Formulation

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Antigen Distribution

CD71 is expressed on the surface of proliferating cells, reticulocytes, and erythroid precursors.

Aggregation

Aggregation level ≤ 5%

Applications Notes

Each investigator should determine their own optimal working dilution for specific applications.

Isotype Control

https://ichor.bio/product/mouse-igg2a-in-vivo-isotype-control-low-endotoxin-c1-18-4-ich2245/