Bulk anti-Human CXCR4 (12G5) Antibody

Catalog number ICH1199-100mg

Price for ICH1199-100mg

Size / count 100 mg

Specifications

Catalog number: ICH1199-100mg
Size / count: 100 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: 12G5 binds specifically to both human and nonhuman cells that express recombinant CXCR4. 12G5 inhibits CD4-independent infection by some HIV-2 isolates, and preincubating cells with 12G5 abolishes syncytium formation. HIV-2/vcp-infected cells display a marked and selective reduction in 12G5 binding. 12G5 also inhibits induction of cell-to-cell fusion of CXCR4+ RD/CD4 cells by HIV-1 and HIV-2 strains.
CAS Number: 9007-83-4
Specifications: 12G5 activity is directed against human CXCR4 (CD184; Fusin)
Product Name Alternative: Fusin, LESTR, CD184
Host: Mouse
Species Reactivity: Human
Target: CXCR4
Isotype: IgG2a Kappa
Clone: 12G5
Applications: Blocking, Flow Cytometry, Immunocytochemistry, Immunofluorescence Microscopy, Immunohistochemistry, Neutralization, Western Blotting
Purification Method: This monoclonal antibody was purified using Protein A
Concentration: ≥ 2.0 mg/mL
Endotoxin: <1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Antigen Distribution: CXCR4 is expressed in various organs including ovary, bone marrow, kidney, lung, small intestine, spleen, lymph nodes, brain, stomach, liver, thymus, heart, and pancreas as well as on the surface of endothelial mature and precursor cells and pericytes.
Aggregation: Aggregation level ≤ 5%
Applications Notes: Each investigator should determine their own optimal working dilution for specific applications.
Isotype Control: https://ichor.bio/product/mouse-igg2a-in-vivo-isotype-control-low-endotoxin-c1-18-4-ich2245/

Frequently Asked Questions

What is the catalog number for Bulk anti-Human CXCR4 (12G5) Antibody?

The catalog number for Bulk anti-Human CXCR4 (12G5) Antibody is ICH1199-100mg.

What sizes are available for Bulk anti-Human CXCR4 (12G5) Antibody?

Bulk anti-Human CXCR4 (12G5) Antibody is available in the following size(s): 100 mg.

Is Bulk anti-Human CXCR4 (12G5) Antibody in stock?

Bulk anti-Human CXCR4 (12G5) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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