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Product details

Eculizumab Biosimilar - Research Grade

Catalog number ICH4005-1mg

Price for ICH4005-1mg

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Size / count 1 mg

Specifications

Catalog number
ICH4005-1mg
Size / count
1 mg
Dry ice
No
Hazardous
No
Discontinued
No
Background
Eculizumab biosimilar is a recombinant humanized monoclonal IgG2/4κ antibody produced by Chinese hamster ovary cell culture and purified by standard bioprocess technology. Eculizumab biosimilar contains human constant regions from human IgG2 sequences and human IgG4 sequences and murine complementarity-determining regions grafted onto the human framework light- and heavy-chain variable regions. Eculizumab biosimilar is composed of two 448 amino acid heavy chains and two 214 amino acid light chains and has a molecular weight of approximately 148 kDa.
Specifications
Detects human Complement protein C5. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Eculizumab.
Product Name Alternative
C5
UniProt
P01031
Host
Humanized
Species Reactivity
Human
Target
Complement protein C5
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0 - 5.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.

Frequently Asked Questions

What is the catalog number for Eculizumab Biosimilar - Research Grade?

The catalog number for Eculizumab Biosimilar - Research Grade is ICH4005-1mg.

What sizes are available for Eculizumab Biosimilar - Research Grade?

Eculizumab Biosimilar - Research Grade is available in the following size(s): 1 mg.

Is Eculizumab Biosimilar - Research Grade in stock?

Eculizumab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

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