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Product details

Nivolumab Biosimilar - Research Grade

Catalog number ICH4009-10mg

Price for ICH4009-10mg

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Size / count 10 mg (2x 5 mg)

Specifications

Catalog number
ICH4009-10mg
Size / count
10 mg (2x 5 mg)
Dry ice
No
Hazardous
No
Discontinued
No
Background
Nivolumab biosimilar is a human monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. Nivolumab is an IgG4 kappa immunoglobulin that has a calculated molecular mass of 146 kDa. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line.
Specifications
Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Nivolumab.
Product Name Alternative
Programmed cell death protein 1, Pdcd1, CD279
UniProt
Q15116
Host
Humanized
Species Reactivity
Human
Target
PD-1
Isotype
IgG4 kappa
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0 - 5.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Isotype Control
https://ichor.bio/product/bulk-human-igg4-isotype-control-ib4-ich2257/

Frequently Asked Questions

What is the catalog number for Nivolumab Biosimilar - Research Grade?

The catalog number for Nivolumab Biosimilar - Research Grade is ICH4009-10mg.

What sizes are available for Nivolumab Biosimilar - Research Grade?

Nivolumab Biosimilar - Research Grade is available in the following size(s): 10 mg (2x 5 mg).

Is Nivolumab Biosimilar - Research Grade in stock?

Nivolumab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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