Ado-Trastuzumab Emtansine Biosimilar - Research Grade

Catalog number ICH4014-5mg

Price for ICH4014-5mg

Size / count 5 mg

Specifications

Catalog number: ICH4014-5mg
Size / count: 5 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
Specifications: Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.
Product Name Alternative: Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
UniProt: P04626
Host: Humanized
Species Reactivity: Human
Target: HER2
Isotype: IgG1
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Isotype Control: https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

Frequently Asked Questions

What is the catalog number for Ado-Trastuzumab Emtansine Biosimilar - Research Grade?

The catalog number for Ado-Trastuzumab Emtansine Biosimilar - Research Grade is ICH4014-5mg.

What sizes are available for Ado-Trastuzumab Emtansine Biosimilar - Research Grade?

Ado-Trastuzumab Emtansine Biosimilar - Research Grade is available in the following size(s): 5 mg.

Is Ado-Trastuzumab Emtansine Biosimilar - Research Grade in stock?

Ado-Trastuzumab Emtansine Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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