Aflibercept Biosimilar - Research Grade

Catalog number ICH4015-20mg

Discontinued

Price for ICH4015-20mg

Size / count 20 mg

This variant is discontinued and cannot be added to your cart.

Specifications

Catalog number: ICH4015-20mg
Size / count: 20 mg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Aflibercept biosimilar is a recombinant fusion protein consisting of portions of human VEGF receptors 1 and 2 extracellular domains fused to the Fc portion of human IgG1 formulated as an iso-osmotic solution for intravitreal administration. Aflibercept biosimilar is a dimeric glycoprotein with a protein molecular weight of 97 kilodaltons (kDa) and contains glycosylation, constituting an additional 15% of the total molecular mass, resulting in a total molecular weight of 115 kDa. Aflibercept biosimilar is produced in recombinant Chinese hamster ovary (CHO) cells.
Specifications: Detects human VEGF. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Aflibercept.
Product Name Alternative: Vascular endothelial growth factor
UniProt: P15692
Host: Humanized
Species Reactivity: Human
Target: VEGF
Isotype: IgG1
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Isotype Control: https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

Frequently Asked Questions

What is the catalog number for Aflibercept Biosimilar - Research Grade?

The catalog number for Aflibercept Biosimilar - Research Grade is ICH4015-20mg.

Is Aflibercept Biosimilar - Research Grade in stock?

Aflibercept Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

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