Alirocumab Biosimilar - Research Grade

Catalog number ICH4016-20mg

Discontinued

Price for ICH4016-20mg

Size / count 20 mg

This variant is discontinued and cannot be added to your cart.

Specifications

Catalog number: ICH4016-20mg
Size / count: 20 mg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: Alirocumab biosimilar is a human monoclonal antibody (IgG1 isotype) that targets proprotein convertase subtilisin kexin type 9 (PCSK9), is a PCSK9 inhibitor produced by recombinant DNA technology in Chinese Hamster Ovary cell suspension culture. Alirocumab biosimilar consists of two disulfide-linked human heavy chains, each covalently linked through a disulfide bond to a human kappa light chain. A single Nlinked glycosylation site is located in each heavy chain within the CH2 domain of the Fc constant region of the molecule. The variable domains of the heavy and light chains combine to form the PCSK9 binding site within the antibody. Alirocumab biosimilar has an approximate molecular weight of 146 kDa.
Specifications: Detects human PCSK9. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Alirocumab.
Product Name Alternative: Proprotein convertase subtilisin/kexin type 9, NARC-1, PC9
UniProt: Q8NBP7
Host: Humanized
Species Reactivity: Human
Target: PCSK9
Isotype: IgG1
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 1.0 - 5.0 mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE and HPLC
Buffer: ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions: Blue ice
Storage Conditions: Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation: Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Isotype Control: https://ichor.bio/product/bulk-human-igg1-isotype-control-ib1-ich2254/

Frequently Asked Questions

What is the catalog number for Alirocumab Biosimilar - Research Grade?

The catalog number for Alirocumab Biosimilar - Research Grade is ICH4016-20mg.

Is Alirocumab Biosimilar - Research Grade in stock?

Alirocumab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.