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Product details

Etanercept Biosimilar - Research Grade

Catalog number ICH4022-10mg

Price for ICH4022-10mg

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Size / count 10 mg (2x 5 mg)

Specifications

Catalog number
ICH4022-10mg
Size / count
10 mg (2x 5 mg)
Dry ice
No
Hazardous
No
Discontinued
No
Background
Etanercept biosimilar is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept biosimilar is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons.
Specifications
Detects human TNF. This non-therapeutic fusion-protein uses the same sequence as the therapeutic Etanercept.
Product Name Alternative
Tumor necrosis factor
UniProt
P01375
Host
Humanized
Species Reactivity
Human
Target
TNF alpha
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
1.0 - 5.0 mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Buffer
ICH3001-100mL ICH3002-100mL ICH3003-100mL
Shipping Conditions
Blue ice
Storage Conditions
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.

Frequently Asked Questions

What is the catalog number for Etanercept Biosimilar - Research Grade?

The catalog number for Etanercept Biosimilar - Research Grade is ICH4022-10mg.

What sizes are available for Etanercept Biosimilar - Research Grade?

Etanercept Biosimilar - Research Grade is available in the following size(s): 10 mg (2x 5 mg).

Is Etanercept Biosimilar - Research Grade in stock?

Etanercept Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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