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Product details

Utomilumab Biosimilar - Research Grade

Catalog number ICH5014-10mg

Price for ICH5014-10mg

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Size / count 10 mg (2x 5 mg)

Specifications

Catalog number
ICH5014-10mg
Size / count
10 mg (2x 5 mg)
Dry ice
No
Hazardous
No
Discontinued
No
Background
RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models.
Specifications
Detects human CD137. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Utomilumab.
Product Name Alternative
4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137
UniProt
Q07011
Species Reactivity
Human
Target
4-1BB
Applications
Functional Assays
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration
5mg/mL
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Buffer
ICH3002
Shipping Conditions
Blue ice
Storage Conditions
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control
https://ichor.bio/product/bulk-human-igg2-isotype-control-ib2-ich2255/

Frequently Asked Questions

What is the catalog number for Utomilumab Biosimilar - Research Grade?

The catalog number for Utomilumab Biosimilar - Research Grade is ICH5014-10mg.

What sizes are available for Utomilumab Biosimilar - Research Grade?

Utomilumab Biosimilar - Research Grade is available in the following size(s): 10 mg (2x 5 mg).

Is Utomilumab Biosimilar - Research Grade in stock?

Utomilumab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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