Utomilumab Biosimilar - Research Grade

Catalog number ICH5014-50mg

Price for ICH5014-50mg

Size / count 50 mg

Specifications

Catalog number: ICH5014-50mg
Size / count: 50 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models.
Specifications: Detects human CD137. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Utomilumab.
Product Name Alternative: 4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137
UniProt: Q07011
Species Reactivity: Human
Target: 4-1BB
Applications: Functional Assays
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 5mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3002
Shipping Conditions: Blue ice
Storage Conditions: This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes: This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control: https://ichor.bio/product/bulk-human-igg2-isotype-control-ib2-ich2255/

Frequently Asked Questions

What is the catalog number for Utomilumab Biosimilar - Research Grade?

The catalog number for Utomilumab Biosimilar - Research Grade is ICH5014-50mg.

What sizes are available for Utomilumab Biosimilar - Research Grade?

Utomilumab Biosimilar - Research Grade is available in the following size(s): 50 mg.

Is Utomilumab Biosimilar - Research Grade in stock?

Utomilumab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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