Atibuclimab Biosimilar - Research Grade

Catalog number ICH5016-100mg

Price for ICH5016-100mg

Size / count 100 mg

Specifications

Catalog number: ICH5016-100mg
Size / count: 100 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates a pro-inflammatory cytokine cascade often associated with inflammation in sepsis. Atibuclimab neutralization of this antibody results in the inhibition of TNF-a, IL-6 and IL-10, dampening systemic inflammatory responses. Atibuclimab also delays the release of sTNFR(1) and IL-1ra.
Specifications: Detects human CD14. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Atibuclimab.
UniProt: P08571
Species Reactivity: Human
Target: CD14
Isotype: IgG4
Applications: Functional Assays
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 5mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3002
Shipping Conditions: Blue ice
Storage Conditions: This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes: This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control: https://ichor.bio/product/bulk-human-igg4-isotype-control-ib4-ich2257/

Frequently Asked Questions

What is the catalog number for Atibuclimab Biosimilar - Research Grade?

The catalog number for Atibuclimab Biosimilar - Research Grade is ICH5016-100mg.

What sizes are available for Atibuclimab Biosimilar - Research Grade?

Atibuclimab Biosimilar - Research Grade is available in the following size(s): 100 mg.

Is Atibuclimab Biosimilar - Research Grade in stock?

Atibuclimab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.