Atibuclimab Biosimilar - Research Grade

Catalog number ICH5016-1mg

Price for ICH5016-1mg

Size / count 1 mg

Specifications

Catalog number: ICH5016-1mg
Size / count: 1 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: RUO atibuclimab is a chimeric CD14 antibody investigated for the treatment of patients with severe sepsis. It acts as a pattern recognition receptor for bacterial cell wall components in gram-positive and negative bacteria. CD14 antibody action stimulates a pro-inflammatory cytokine cascade often associated with inflammation in sepsis. Atibuclimab neutralization of this antibody results in the inhibition of TNF-a, IL-6 and IL-10, dampening systemic inflammatory responses. Atibuclimab also delays the release of sTNFR(1) and IL-1ra.
Specifications: Detects human CD14. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Atibuclimab.
UniProt: P08571
Species Reactivity: Human
Target: CD14
Isotype: IgG4
Applications: Functional Assays
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 5mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3002
Shipping Conditions: Blue ice
Storage Conditions: This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes: This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control: https://ichor.bio/product/bulk-human-igg4-isotype-control-ib4-ich2257/

Frequently Asked Questions

What is the catalog number for Atibuclimab Biosimilar - Research Grade?

The catalog number for Atibuclimab Biosimilar - Research Grade is ICH5016-1mg.

What sizes are available for Atibuclimab Biosimilar - Research Grade?

Atibuclimab Biosimilar - Research Grade is available in the following size(s): 1 mg.

Is Atibuclimab Biosimilar - Research Grade in stock?

Atibuclimab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.