Theralizumab Biosimilar - Research Grade

Catalog number ICH5023-1mg

Price for ICH5023-1mg

Size / count 1 mg

Specifications

Catalog number: ICH5023-1mg
Size / count: 1 mg
Dry ice: No
Hazardous: No
Discontinued: No
Background: Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Specifications: Detects human CD28. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Theralizumab.
Product Name Alternative: TGN1412, CD28-SuperMAB, TAB08
UniProt: P10747
Species Reactivity: Human
Target: CD28
Isotype: IgG4
Applications: Functional Assays
Purification Method: This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Concentration: 5mg/mL
Endotoxin: ≤ 1.0 EU/mg as determined by the LAL method
Purity: >95% by SDS-PAGE
Buffer: ICH3002
Shipping Conditions: Blue ice
Storage Conditions: This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation: Sterile, preservative-free, solution in PBS. BSA and Azide free.
Applications Notes: This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Isotype Control: https://ichor.bio/product/bulk-human-igg4-isotype-control-ib4-ich2257/

Frequently Asked Questions

What is the catalog number for Theralizumab Biosimilar - Research Grade?

The catalog number for Theralizumab Biosimilar - Research Grade is ICH5023-1mg.

What sizes are available for Theralizumab Biosimilar - Research Grade?

Theralizumab Biosimilar - Research Grade is available in the following size(s): 1 mg.

Is Theralizumab Biosimilar - Research Grade in stock?

Theralizumab Biosimilar - Research Grade is currently made to order / not held in immediate stock. Contact us for lead time.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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