B7-2/CD86 Polyclonal Antibody — image 1 of 2

Product details

B7-2/CD86 Polyclonal Antibody

Catalog number AN007150L-01

Discontinued

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Price for AN007150L-01

Size / count 25 µL

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Specifications

Catalog number: AN007150L-01
Size / count: 25 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant costimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20‑100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response. B7-1 is expressed on activated B cells, activated T cells, and macrophages. B7-2 is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B7-2 is expressed at low levels on monocytes and can be up-regulated through interferon gamma. B7-1 and B7-2 are both members of the immunoglobulin superfamily.
Abbreviation: CD86
UniProt: O35531
Host: Rabbit
Reactivity: Human
Immunogen: Recombinant Rat B7-2/CD86 protein expressed by Mammalian
Target: Activation B7-2 antigen; B72; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD86 antigen; CD86 molecule; CD86; CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86; CD28LG2B7-2 antigen) ; CD28 antigen ligand 2
Clonality: Polyclonal
Conjugation: Unconjugated
Applications: WB; IHC
Purification: Antigen Affinity Purification
Concentration: 1 mg/mL
Dilution: WB 1:500-1:1000; IHC 1:200-1:400
Buffer: PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions: The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight: 37KDa
Observed Molecular Weight: 75kDa
Isotype: IgG

Frequently Asked Questions

What is the catalog number for B7-2/CD86 Polyclonal Antibody?

The catalog number for B7-2/CD86 Polyclonal Antibody is AN007150L.

What sizes are available for B7-2/CD86 Polyclonal Antibody?

B7-2/CD86 Polyclonal Antibody is available in the following size(s): 25 µL, 100 µL.

How many pack sizes does B7-2/CD86 Polyclonal Antibody come in?

B7-2/CD86 Polyclonal Antibody is available in 2 different pack sizes.

Is B7-2/CD86 Polyclonal Antibody in stock?

B7-2/CD86 Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures B7-2/CD86 Polyclonal Antibody?

B7-2/CD86 Polyclonal Antibody is manufactured by Elabscience.

What is the estimated delivery time for B7-2/CD86 Polyclonal Antibody?

Estimated delivery time for B7-2/CD86 Polyclonal Antibody is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for B7-2/CD86 Polyclonal Antibody?

The safety data sheet for B7-2/CD86 Polyclonal Antibody is available here: https://789.bio/eb/OVHdqP.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.