Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95]

Catalog number HA722472

Price for HA722472

Size / count 100 µL

About this product

Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.

Specifications

Catalog number: HA722472
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 130 kDa retinoblastoma associated protein antibody 130 kDa retinoblastoma-associated protein antibody IB4 antibody p130 antibody PPAR-alpha-interacting complex protein 128 antibody PRB2 antibody Rb2 antibody Rbl2 antibody RBL2_HUMAN antibody RBR 2 antibody RBR-2 antibody RBR2 antibody Retinoblastoma like 2 antibody Retinoblastoma-like protein 2 antibody Retinoblastoma-related protein 2 antibody RIC128 antibody
Abbreviation: Retinoblastoma-like protein 2 130 kDa retinoblastoma-associated protein (p130) Retinoblastoma-related protein 2 (RBR-2) pRb2 RBL2 RB2
Swiss Prot: Q08999 Human, Q64700 Mouse, O55081 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phosphopeptide corresponding to residues around Thr986 of human p130.
Isotype: IgG
Clone: JE64-95
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Jurkat cell lysate, K-562 cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, PC-12 cell lysate, human appendix tissue, human colon cancer tissue, mouse colon tissue, rat colon tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 128 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95]?

The catalog number for Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95] is HA722472.

What sizes are available for Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95]?

Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95] is available in the following size(s): 100 µL.

Is Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95] in stock?

Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-p130 (T986) Recombinant Rabbit Monoclonal Antibody [JE64-95] used for?

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.