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![SCIN Recombinant Rabbit Monoclonal Antibody [JE62-89] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81cca/imageurl/ha722465.webp)
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Product details
Catalog number HA722465
Price for HA722465
Size / count 100 µL
Ca2+-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles. Plays a role in osteoclastogenesis (OCG) and actin cytoskeletal organization in osteoclasts. Regulates chondrocyte proliferation and differentiation. Inhibits cell proliferation and tumorigenesis. Signaling is mediated by MAPK, p38 and JNK pathways.
The catalog number for SCIN Recombinant Rabbit Monoclonal Antibody [JE62-89] is HA722465.
SCIN Recombinant Rabbit Monoclonal Antibody [JE62-89] is available in the following size(s): 100 µL.
SCIN Recombinant Rabbit Monoclonal Antibody [JE62-89] is currently made to order / not held in immediate stock. Contact us for lead time.
Ca2+-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate (PIP2) (By similarity). In vitro, also has b
Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.
