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Product details

Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68]

Catalog number HA722391

Price for HA722391

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Size / count 100 µL

About this product

Reticulon 4 receptor (RTN4R) also known as Nogo-66 Receptor (NgR) or Nogo receptor 1 is a protein which in humans is encoded by the RTN4R gene. This gene encodes the receptor for reticulon 4, oligodendrocytemyelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth inhibition and may play a role in regulating axonal regeneration and plasticity in the adult central nervous system. The Nogo-66 Receptor (NgR) is a high affinity binding receptor for a region of Nogo, a myelin associated protein that inhibits axon outgrowth. NgR was identified by Strittmatter and colleagues using an expression cloning strategy. NgR is implicated in neuronal plasticity and regeneration. Its relative importance in mediating myelin inhibition in vitro and in vivo is currently under intense investigation, since this protein might be a good drug target for treatment of various neurological conditions such as spinal cord injury and stroke.

Specifications

Catalog number
HA722391
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
NgR antibody Nogo 66 receptor antibody Nogo receptor antibody Nogor antibody Reticulon 4 receptor antibody Rtn4r antibody UNQ330/PRO526 antibody
Abbreviation
RTN4R, NOGOR
Swiss Prot
Q9BZR6 Human, Q99PI8 Mouse, Q99M75 Rat
Cellular Locus
Cell membrane, Membrane raft, Cell projection, dendrite, axon, Perikaryon.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Nogo Receptor aa 341-440 / 473.
Isotype
IgG
Clone
JE33-68
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
SH-SY5Y cell lysate, HepG2 cell lysate, HEK-293 cell lysate, C6 cell lysate, mouse brain tissue lysate, rat brain tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 51 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68]?

The catalog number for Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68] is HA722391.

What sizes are available for Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68]?

Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68] is available in the following size(s): 100 µL.

Is Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68] in stock?

Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Nogo Receptor Recombinant Rabbit Monoclonal Antibody [JE33-68] used for?

Reticulon 4 receptor (RTN4R) also known as Nogo-66 Receptor (NgR) or Nogo receptor 1 is a protein which in humans is encoded by the RTN4R gene. This gene encodes the receptor for reticulon 4, oligodendrocytemyelin glycoprotein and myelin-associated glycoprotein. This receptor mediates axonal growth

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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