Integrin beta 3 Recombinant Rabbit Monoclonal Antibody [PSH09-27]

About this product

Integrin beta-3 (β3) or CD61 is a protein that in humans is encoded by the ITGB3 gene. CD61 is a cluster of differentiation found on thrombocytes. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface-mediated signaling. Defectively expressed β3 integrin subunit has been correlated with presence of endometriosis, and has been suggested as a putative marker of this condition.

Specifications

Catalog number

HA723085

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

BDPLT16 antibody BDPLT2 antibody CD 61 antibody CD61 antibody CD61 antigen antibody GP3A antibody GPIIIa antibody GT antibody HPA 1 antibody HPA 4 antibody Integrin beta 3 (platelet glycoprotein IIIa antigen CD61) antibody Integrin beta chain beta 3 antibody Integrin beta-3 antibody ITB3_HUMAN antibody ITG B3 antibody ITGB 3 antibody ITGB3 antibody NAIT antibody platelet fibrinogen receptor antibody Platelet fibrinogen receptor beta subunit antibody Platelet fibrinogen receptor, beta subunit antibody Platelet glycoprotein IIIa antibody Platelet glycoprotein IIIa precursor antibody Platelet membrane glycoprotein IIIa antibody PTP antibody

Abbreviation

Integrin beta-3 Platelet membrane glycoprotein IIIa (GPIIIa) CD61 ITGB3 GP3A

Swiss Prot

P05106 Human, O54890 Mouse,

Cellular Locus

Cell membrane, Cell projection, lamellipodium membrane, Cell junction, focal adhesion, Postsynaptic cell membrane, Synapse.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human Integrin beta 3 aa 101-150.

Isotype

IgG

Clone

PSH09-27

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

U-87 MG cell lysate, LNCaP cell lysate, HUVEC cell lysate, C2C12 cell lysate, Mouse spleen tissue lysate, Rat spleen tissue lysate, human kidney tissue, human spleen tissue, mouse spleen tissue, rat spleen tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IHC-P: 1:2,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 87 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes