TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93]

Catalog number HA721531

Price for HA721531

Size / count 100 µL

About this product

Tyrosyl-DNA phosphodiesterase 1 is an enzyme that in humans is encoded by the TDP1 gene. The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of Type I topoisomerase and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same isoform.

Specifications

Catalog number: HA721531
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AI838772 antibody AW493413 antibody FLJ11090 antibody MGC104252 antibody MGC112732 antibody RP24-311F12.2 antibody SCAN1 antibody TDP1 antibody TYDP antibody TYDP1_HUMAN antibody Tyr-DNA phosphodiesterase 1 antibody Tyrosyl-DNA phosphodiesterase 1 antibody
Abbreviation: TDP1
Swiss Prot: Q9NUW8 Human, Q8BJ37 Mouse, Q4G056 Rat
Cellular Locus: Nucleus, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human TDP1 aa 100-608 / 608.
Isotype: IgG
Clone: PSH0-93
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: MCF7 cell lysate, HEK-293 cell lysate, HeLa cell lysate, A375 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, human brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 68 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93]?

The catalog number for TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93] is HA721531.

What sizes are available for TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93]?

TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93] is available in the following size(s): 100 µL.

Is TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93] in stock?

TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TDP1 Recombinant Rabbit Monoclonal Antibody [PSH0-93] used for?

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.