SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52]

Catalog number HA721337

Price for HA721337

Size / count 100 µL

About this product

Sortilin-related receptor, L (DLR class) A repeats containing is a protein that in humans is encoded by the SORL1 gene. SORL1 (also known as SORLA, SORLA1, or LR11) is a neuronal apolipoprotein E receptor, the gene for which is predominantly expressed in the central nervous system. Mutation of the gene for apolipoprotein E (APOE) is predictive of Alzheimer's disease. Lack of the APOE receptor is suspected to be a contributory factor to Alzheimer's: a significant reduction in SORL1 (LR11) expression has been found in brain tissue of Alzheimer's disease patients. The APOE receptor has also been linked with regulation of amyloid precursor protein, faulty processing of which is implicated in Alzheimer's. A more recent study by a group of international researchers supports the proposition that SORL1 plays a part in seniors developing Alzheimer's disease, the findings being significant across racial and ethnic strata.

Specifications

Catalog number: HA721337
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: C11orf32 antibody FLJ21930 antibody FLJ39258 antibody gp250 antibody LDLR relative with 11 ligand binding repeats antibody LDLR relative with 11 ligand-binding repeats antibody Low density lipoprotein receptor relative with 11 ligand binding repeats antibody Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody LR 11 antibody LR11 antibody LRP 9 antibody LRP9 antibody Mosaic protein LR11 antibody SORL 1 antibody SORL_HUMAN antibody SORL1 antibody SorLA 1 antibody SorLA antibody SorLA-1 antibody Sortilin related receptor antibody Sortilin related receptor L (DLR class) A repeats containing antibody Sortilin-related receptor antibody Sorting protein related receptor containing LDLR class A repeats antibody Sorting protein-related receptor containing LDLR class A repeats antibody
Abbreviation: SORL1
Swiss Prot: Q92673 Human, O88307 Mouse, Q9R0N2 Rat
Cellular Locus: Cell membrane, Cytoplasmic vesicle, Endoplasmic reticulum, Endosome, Golgi apparatus, Membrane, Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human SorLA aa 1,341-1,540 / 2,214.
Isotype: IgG
Clone: JE35-52
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Jurkat cell lysates, mouse cerebellum tissue, rat cerebellum tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 248 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52]?

The catalog number for SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52] is HA721337.

What sizes are available for SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52]?

SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52] is available in the following size(s): 100 µL.

Is SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52] in stock?

SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SorLA Recombinant Rabbit Monoclonal Antibody [JE35-52] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

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Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.