GMP Human TGF-Beta 1 / TGFB1 Protein

Catalog number GMP-TG1H25-500ug

Discontinued

Price for GMP-TG1H25-500ug

Size / count 500 µg

This variant is discontinued and cannot be added to your cart.

About this product

GMP Human TGF-Beta 1 Protein (GMP-TG1H25) is expressed from human 293 cells (HEK293). It contains AA Ala 279 - Ser 390 (Accession # P01137-1).

Specifications

Catalog number: GMP-TG1H25-500ug
Size / count: 500 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
Specifications: This protein carries no "tag". The protein has a calculated MW of 12.8 kDa. The protein migrates as 13 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Expression Region: Ala 279 - Ser 390
Host: HEK 293
Target: TGF-beta 1
Conjugation: Unconjugated
Tag: Native
Source: Human
Stability: -20°C to -70°C for 5 years in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution._x000D_Upon receipt, store it immediately at -20°C or lower for long term storage.
Endotoxin: 10 EU/mg
Purity: 95%
Format: Powder-GMP
Buffer: 100 mM HAC, pH3.0
Molecular Weight: 12.8 kDa
Shipping Conditions: Blue ice
Storage Conditions: -20°C

Frequently Asked Questions

What is the catalog number for GMP Human TGF-Beta 1 / TGFB1 Protein?

The catalog number for GMP Human TGF-Beta 1 / TGFB1 Protein is GMP-TG1H25-500ug.

Is GMP Human TGF-Beta 1 / TGFB1 Protein in stock?

GMP Human TGF-Beta 1 / TGFB1 Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GMP Human TGF-Beta 1 / TGFB1 Protein?

GMP Human TGF-Beta 1 / TGFB1 Protein is manufactured by CRB.

What is the estimated delivery time for GMP Human TGF-Beta 1 / TGFB1 Protein?

Estimated delivery time for GMP Human TGF-Beta 1 / TGFB1 Protein is approximately 10 business day(s), depending on your location.

What is GMP Human TGF-Beta 1 / TGFB1 Protein used for?

GMP Human TGF-Beta 1 Protein (GMP-TG1H25) is expressed from human 293 cells (HEK293). It contains AA Ala 279 - Ser 390 (Accession # P01137-1).

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.