PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96]

Catalog number HA721962

Price for HA721962

Size / count 100 µL

About this product

As human tumors progress to advanced stages, one genetic alteration that occurs at high frequency is a loss of heterozygosity (LOH) at chromosome 10q23. Mapping of homozygous deletions on this chromosome led to the isolation of the PTEN gene, also designated MMAC1 (for mutated in multiple advanced cancers) and TEP1. This candidate tumor suppressor gene exhibits a high frequency of mutations in human glioblastomas and is also mutated in other cancers, including sporadic brain, breast, kidney and prostate cancers. PTEN has been associated with Cowden disease, an autosomal dominant cancer predisposition syndrome. The PTEN gene product is a putative protein tyrosine phosphatase that is localized to the cytoplasm and shares extensive homology with the cytoskeletal proteins tensin and auxilin. Gene transfer studies have indicated that the phosphatase domain of PTEN is essential for growth suppression of glioma cells.

Specifications

Catalog number: HA721962
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 10q23del antibody BZS antibody DEC antibody GLM2 antibody MGC11227 antibody MHAM antibody MMAC1 antibody MMAC1 phosphatase and tensin homolog deleted on chromosome 10 antibody Mutated in multiple advanced cancers 1 antibody Phosphatase and tensin homolog antibody Phosphatase and tensin like protein antibody Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN antibody Pten antibody PTEN_HUMAN antibody PTEN1 antibody TEP1 antibody
Abbreviation: PTEN
Swiss Prot: P60484 Human, O08586 Mouse
Cellular Locus: Cytoplasm, Nucleus, Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant full length protein of Human PTEN.
Isotype: IgG
Clone: JE51-96
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: HeLa cell lysate, MCF7 cell lysate, A431 cell lysate, NIH/3T3 cell lysate, C6 cell lysate, PC-12 cell lysate, mouse brain tissue, rat brain tissue, A431, C6.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:500 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 47 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96]?

The catalog number for PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96] is HA721962.

What sizes are available for PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96]?

PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96] is available in the following size(s): 100 µL.

Is PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96] in stock?

PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PTEN Recombinant Rabbit Monoclonal Antibody [JE51-96] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.