Anti-HtrA2/Omi Antibody

Catalog number A01941-1

Price for A01941-1

Size / count 100 µL

About this product

Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number: A01941-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: HTRA2; OMI; PRSS25; Serine protease HTRA2; mitochondrial; High temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; Serine protease 25; Serine proteinase OMI
Gene Name: HTRA2
UniProt: O43464
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: A peptide derived from human HtrA2. Immunogen sequence location: 181-230
Clonality: Polyclonal
Tissue Specificity: Isoform 1 is ubiquitous.Isoform 2 is expressed predominantly in the kidney, colon and thyroid.
Applications: IHC-P, IF (paraffin), ELISA
Field of Research: Apoptosis, Cancer, Cell Biology, Cell Death, Invasion/Microenvironment, Metabolism, Metabolism Processes, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Neurodegenerative Disease, Neurology Process, Neuroscience, Oxidative Stress, Pathways and Processes, Redox Metabolism
Purification: The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Function: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.
Molecular Weight: 48841 MW
Shipping Conditions: Available
Storage Conditions: Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Other Gene Names: Serine protease HTRA2, mitochondrial
Subcellular Location: Mitochondrion intermembrane space. Mitochondrion membrane; Single-pass membrane protein. Predominantly present in the intermembrane space. Released into the cytosol following apoptotic stimuli, such as UV treatment, and stimulation of mitochondria with caspase-8 truncated BID/tBID.

Frequently Asked Questions

What is the catalog number for Anti-HtrA2/Omi Antibody?

The catalog number for Anti-HtrA2/Omi Antibody is A01941-1.

What sizes are available for Anti-HtrA2/Omi Antibody?

Anti-HtrA2/Omi Antibody is available in the following size(s): 100 µL.

Is Anti-HtrA2/Omi Antibody in stock?

Anti-HtrA2/Omi Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-HtrA2/Omi Antibody?

The safety data sheet for Anti-HtrA2/Omi Antibody is available here: https://www.bosterbio.com/msds?sku=A01941-1.

What is Anti-HtrA2/Omi Antibody used for?

Boster Bio Anti-HtrA2/Omi Antibody (Catalog# A01941-1) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.