Anti-MRF2 ARID5B Antibody

Catalog number A02880

Price for A02880

Size / count 100 µg

About this product

Boster Bio Anti-MRF2 ARID5B Antibody (Catalog# A02880) . Tested in WB application (s) . This antibody reacts with Human.

Specifications

Catalog number: A02880
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: AT-rich interactive domain-containing protein 5B; ARID domain-containing protein 5B; MRF1-like protein; Modulator recognition factor 2; MRF-2; ARID5B; DESRT, MRF2
Gene Name: ARID5B
UniProt: Q14865
Host: Rabbit
Reactivity: Human
Immunogen: A partial length recombinant MRF2 protein (amino acids 430-621)
Clonality: Polyclonal
Tissue Specificity: Widely expressed, including in liver (at protein level) .
Applications: WB
Field of Research: Chromatin Binding Proteins, DNA/RNA Binding, Epigenetics and Nuclear Signaling, Transcription, Transcription Factors
Purification: Protein A Chromatography
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution: Western blot: 1-2 µg/ml
Form: Liquid
Function: Transcription coactivator that binds to the 5'-AATA[CT]- 3' core sequence and plays a key role in adipogenesis and liver development. Acts by forming a complex with phosphorylated PHF2, which mediates demethylation at Lys-336, leading to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2- ARID5B complex acts as a coactivator of HNF4A in liver. Required for adipogenesis: regulates triglyceride metabolism in adipocytes by regulating expression of adipogenic genes. Overexpression leads to induction of smooth muscle marker genes, suggesting that it may also act as a regulator of smooth muscle cell differentiation and proliferation. Represses the cytomegalovirus enhancer. .
Molecular Weight: 132375 MW
Shipping Conditions: Available
Storage Conditions: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Fragment: Rabbit IgG
Other Gene Names: AT-rich interactive domain-containing protein 5B
Subcellular Location: Nucleus.
Protein Name: AT-rich interactive domain-containing protein 5B

Frequently Asked Questions

What is the catalog number for Anti-MRF2 ARID5B Antibody?

The catalog number for Anti-MRF2 ARID5B Antibody is A02880.

What sizes are available for Anti-MRF2 ARID5B Antibody?

Anti-MRF2 ARID5B Antibody is available in the following size(s): 100 µg.

Is Anti-MRF2 ARID5B Antibody in stock?

Anti-MRF2 ARID5B Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MRF2 ARID5B Antibody?

The safety data sheet for Anti-MRF2 ARID5B Antibody is available here: https://www.bosterbio.com/msds?sku=A02880.

What is Anti-MRF2 ARID5B Antibody used for?

Boster Bio Anti-MRF2 ARID5B Antibody (Catalog# A02880) . Tested in WB application (s) . This antibody reacts with Human.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.