Anti-DEDD2 (DED4) Antibody

Catalog number A11263

Price for A11263

Size / count 50 µL

About this product

Boster Bio Anti-DEDD2 (DED4) Antibody (Catalog# A11263) . Tested in WB application (s) . This antibody reacts with Canine, Rat, Mouse, Human.

Specifications

Catalog number: A11263
Size / count: 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: DNA-binding death effector domain-containing protein 2; DED-containing protein FLAME-3; FADD-like anti-apoptotic molecule 3; DEDD2; FLAME3; PSEC0004
Gene Name: DEDD2
UniProt: Q8WXF8
Host: Rabbit
Reactivity: Canine, Rat, Mouse, Human
Immunogen: A synthetic peptide of DEDD2 (DED4) protein (amino acids 210-228 GPALEQGVASRRPQALARQ)
Clonality: Polyclonal
Tissue Specificity: Expressed in most tissues. High levels were found in liver, kidney, heart, ovary, spleen, testes, skeletal muscle and peripheral blood leukocytes. Expression was absent or low in colon and small intestine. Expression is relatively high in the tumor cell lines chronic myologenous leukemia K-562 and the colorectal adenocarcinoma SW480. Expression is moderate in the cervical carcinoma HeLa, the Burkitt's lymphoma Raji, the lung carcinoma A-549, and the melanoma G-361. In contrast, two leukemia cell lines, HL-60 (promyelocytic leukemia) and MOLT-4 (lymphoblastic leukemia), show relatively low levels.
Applications: WB
Field of Research: Apoptosis, Cell Biology, Receptors
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution: WB: 1:1000-1:5000
Form: Liquid
Function: May play a critical role in death receptor-induced apoptosis and may target CASP8 and CASP10 to the nucleus. May regulate degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3.
Molecular Weight: 36179 MW
Shipping Conditions: Available
Storage Conditions: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Fragment: Rabbit IgG
Other Gene Names: DNA-binding death effector domain-containing protein 2
Subcellular Location: Nucleus, nucleolus. Nuclear, accumulated in subnuclear structures resembling nucleoli.
Protein Name: DNA-binding death effector domain-containing protein 2

Frequently Asked Questions

What is the catalog number for Anti-DEDD2 (DED4) Antibody?

The catalog number for Anti-DEDD2 (DED4) Antibody is A11263.

What sizes are available for Anti-DEDD2 (DED4) Antibody?

Anti-DEDD2 (DED4) Antibody is available in the following size(s): 50 µL.

Is Anti-DEDD2 (DED4) Antibody in stock?

Anti-DEDD2 (DED4) Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-DEDD2 (DED4) Antibody?

The safety data sheet for Anti-DEDD2 (DED4) Antibody is available here: https://www.bosterbio.com/msds?sku=A11263.

What is Anti-DEDD2 (DED4) Antibody used for?

Boster Bio Anti-DEDD2 (DED4) Antibody (Catalog# A11263) . Tested in WB application (s) . This antibody reacts with Canine, Rat, Mouse, Human.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.