Anti-ASC2 (ASC-2/POP) PYDC1 Antibody

About this product

Boster Bio Anti-ASC2 (ASC-2/POP) PYDC1 Antibody (Catalog# A11388) . Tested in IP, IHC, WB application (s) . This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

A11388

Size / count

50 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Pyrin domain-containing protein 1; PAAD-only protein 1; Pyrin-only protein 1; cellular POP1; cPOP1; PYDC1; ASC2 , ASCI, POP1 , PYC1

Gene Name

PYDC1

UniProt

Q8WXC3

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A full-length recombinant protein of ASC2 (ASC-2/POP)

Clonality

Polyclonal

Tissue Specificity

Predominantly expressed in monocytes, macrophages and granulocytes.

Applications

IP, IHC, WB

Field of Research

Cell Biology

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Associates with PYCARD/ASC and modulates its ability to collaborate with MEFV/pyrin and NLRP3/cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS. .

Molecular Weight

10107 MW

Shipping Conditions

Available

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Pyrin domain-containing protein 1

Subcellular Location

Cytoplasm. Recruited to specks formed by PYCARD within the cytoplasm.

Protein Name

Pyrin domain-containing protein 1