Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated

Catalog number FC00591-Biotin

Discontinued

Price for FC00591-Biotin

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00591-Biotin) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: FC00591-Biotin
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: CD71 is also known as transferrin receptor (TFRC) . Nikinmaa and Schroder (1987) concluded that p90 and TFRC are the same protein: studies using monoclonal antibodies indicated that exhaustive precipitation of radioactively labeled lysates with one antibody removed all activity of lysates with the other. Peptide maps of antigens recognized with both antibodies showed great similarity and indicated that both antibodies react with the same antigen, the human transferrin receptor, but with different antigenic sites of the molecule.TFR is assigned to chromosome 3.
Synonyms: Transferrin receptor protein 1; TR; TfR; TfR1; Trfr; T9; p90; CD71; Transferrin receptor protein 1, serum form; sTfR; TFRC
Gene Name: TFRC
UniProt: P02786
Host: Mouse
Reactivity: Human
Immunogen: Human acute lymphoblastic leukaemia cells
Clonality: Monoclonal
Clone: Clone: Clone: OKT9
Conjugation: Biotin
Applications: Flow Cytometry
Field of Research: Cancer, Cancer Metabolism, Cardiovascular, Cell Type Markers, Hematopoietic Progenitors, Immunology, Lymphoid, Metabolism, Metabolism Processes, Myeloid, Neural Stem Cells, Pathways and Processes, Response To Hypoxia, Serum Proteins, Stem Cells, Surface Molecules, T Lymphocytic Lineage
Purification: Protein A purified
Sensitivity: 5ul per sample
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution: User needs to optimize the dilution ratio for this antibody.
Form: Liquid
Function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity) . A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. .
Molecular Weight: 84871 MW
Shipping Conditions: Available
Storage Conditions: Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Fragment: IgG1, k
Other Gene Names: Transferrin receptor protein 1
Subcellular Location: Cell membrane; Single-pass type II membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Protein Name: Transferrin receptor protein 1

Frequently Asked Questions

What is the catalog number for Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated?

The catalog number for Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated is FC00591-Biotin.

Is Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated in stock?

Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated?

The safety data sheet for Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated is available here: https://www.bosterbio.com/msds?sku=FC00591-Biotin.

What is Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated used for?

Boster Bio Anti-human CD71 TFRC Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC00591-Biotin) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.