Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated

Catalog number FC02236-Biotin

Discontinued

Price for FC02236-Biotin

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC02236-Biotin) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

Specifications

Catalog number: FC02236-Biotin
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.
Synonyms: T-cell surface glycoprotein CD8 alpha chain; T-cell surface glycoprotein Lyt-2; CD8a; Cd8a; Lyt-2, Lyt2
Gene Name: Cd8a
UniProt: P01732
Host: Mouse
Reactivity: Human
Immunogen: Human peripheral blood T lymphocytes
Clonality: Monoclonal
Clone: Clone: Clone: OKT8
Conjugation: Biotin
Applications: Flow Cytometry
Field of Research: Adaptive Immunity, Immunology, T Cells
Purification: Protein A purified
Sensitivity: 5ul per sample
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Dilution: User needs to optimize the dilution ratio for this antibody.
Form: Liquid
Function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Molecular Weight: 27456 MW
Shipping Conditions: Available
Storage Conditions: Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Fragment: IgG2a, k
Other Gene Names: T-cell surface glycoprotein CD8 alpha chain
Subcellular Location: Membrane; Single-pass type I membrane protein.
Protein Name: T-cell surface glycoprotein CD8 alpha chain

Frequently Asked Questions

What is the catalog number for Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated?

The catalog number for Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated is FC02236-Biotin.

Is Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated in stock?

Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated?

The safety data sheet for Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated is available here: https://www.bosterbio.com/msds?sku=FC02236-Biotin.

What is Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated used for?

Boster Bio Anti-human CD8 Cd8a Monoclonal Antibody Biotin Conjugated, Flow Validated (Catalog# FC02236-Biotin) . Tested in Flow Cytometry application (s) . This antibody reacts with Human.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.