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Product details

Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348

Catalog number M00084-2

Price for M00084-2

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Size / count 100 µL

About this product

Boster Bio Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 (Catalog # M00084-2) . Tested in IHC, WB applications. This antibody reacts with Human.

Specifications

Catalog number
M00084-2
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Prostaglandin G/H synthase 2;1.14.99.1; Cyclooxygenase-2; COX-2; PHS II; Prostaglandin H2 synthase 2; PGH synthase 2; PGHS-2; Prostaglandin-endoperoxide synthase 2; PTGS2; COX2
Gene Name
PTGS2
UniProt
P35354
Host
Rabbit
Reactivity
Human
Cross Reactivity
This antibody reacts to human COX-2 (Prostaglandin G/H synthase 2) .
Immunogen
A peptide corresponding to the C-terminus of human COX-2.
Clonality
Monoclonal
Clone
Clone: RM348
Applications
IHC, WB
Field of Research
Atherosclerosis, Cancer, Cancer Metabolism, Cardiovascular, Cholesterol Metabolism, Endocrine Metabolism, Heart Disease, Hormone Biosynthesis, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Platelets, Signal Transduction, Signaling Pathway, Tumor Biomarkers
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Concentration
0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form
Liquid
Function
Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.
Molecular Weight
68996 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
Prostaglandin G/H synthase 2
Subcellular Location
Microsome membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein.

Frequently Asked Questions

What is the catalog number for Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348?

The catalog number for Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 is M00084-2.

What sizes are available for Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348?

Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 is available in the following size(s): 100 µL.

Is Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 in stock?

Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348?

The safety data sheet for Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 is available here: https://www.bosterbio.com/msds?sku=M00084-2.

What is Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 used for?

Boster Bio Anti-COX-2 PTGS2 Rabbit Monoclonal Antibody, Clone#RM348 (Catalog # M00084-2) . Tested in IHC, WB applications. This antibody reacts with Human.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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