Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268

Catalog number M00468-1

Price for M00468-1

Size / count 100 µL

About this product

Boster Bio Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 (Catalog # M00468-1) . Tested in IHC, WB applications. This antibody reacts with Human.

Specifications

Catalog number: M00468-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Integrin alpha-4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; CD49d; ITGA4; CD49D
Gene Name: ITGA4
UniProt: P13612
Host: Rabbit
Reactivity: Human
Cross Reactivity: This antibody reacts to the cytoplasmic domain of human Integrin alpha 4 (ITGA4) .
Immunogen: A peptide corresponding to the C-terminus of human Integrin alpha 4 (ITGA4) .
Clonality: Monoclonal
Clone: Clone: RM268
Applications: IHC, WB
Field of Research: Cell Adhesion, Cell Type Markers, Cytoskeleton/ECM, Immunology, Integrins, Neural Stem Cells, Signal Transduction, Stem Cells, Surface Molecules
Purification: Protein A affinity purified from an animal origin-free culture supernatant
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Function: Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha- 4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha- 4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. ITGA4:ITGB1 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415) . ITGA4:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877) .
Molecular Weight: 114900 MW
Shipping Conditions: Available
Storage Conditions: Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Other Gene Names: Integrin alpha-4
Subcellular Location: Membrane; Single-pass type I membrane protein.

Frequently Asked Questions

What is the catalog number for Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268?

The catalog number for Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 is M00468-1.

What sizes are available for Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268?

Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 is available in the following size(s): 100 µL.

Is Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 in stock?

Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268?

The safety data sheet for Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 is available here: https://www.bosterbio.com/msds?sku=M00468-1.

What is Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 used for?

Boster Bio Anti-Integrin alpha 4 (ITGA4) Rabbit Monoclonal Antibody, Clone#RM268 (Catalog # M00468-1) . Tested in IHC, WB applications. This antibody reacts with Human.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.