Anti-Stathmin (STMN1) Rabbit Monoclonal Antibody, Clone#RM350

About this product

Boster Bio Anti-Stathmin (STMN1) Rabbit Monoclonal Antibody, Clone#RM350 (Catalog # M01194-1) . Tested in IHC, WB applications. This antibody reacts with Human.

Specifications

Catalog number

M01194-1

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Stathmin; Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; Phosphoprotein p19; pp19; Prosolin; Protein Pr22; pp17; STMN1; C1orf215, LAP18, OP18

Gene Name

STMN1

UniProt

P16949

Host

Rabbit

Reactivity

Human

Cross Reactivity

This antibody reacts to human Stathmin. It may also react to mouse or rat Stathmin, as predicted by immunogen homology.

Immunogen

A peptide corresponding to the C-terminus of human Stathmin.

Clonality

Monoclonal

Clone

Clone: RM350

Tissue Specificity

Ubiquitous. Expression is strongest in fetal and adult brain, spinal cord, and cerebellum, followed by thymus, bone marrow, testis, and fetal liver. Expression is intermediate in colon, ovary, placenta, uterus, and trachea, and is readily detected at substantially lower levels in all other tissues examined. Lowest expression is found in adult liver. Present in much greater abundance in cells from patients with acute leukemia of different subtypes than in normal peripheral blood lymphocytes, non-leukemic proliferating lymphoid cells, bone marrow cells, or cells from patients with chronic lymphoid or myeloid leukemia.

Applications

IHC, WB

Field of Research

Alzheimer's Disease, Cell Adhesion Proteins, Cytoskeleton, Cytoskeleton/ECM, Microtubules, Neurodegenerative Disease, Neurology Process, Neuroscience, Signal Transduction, Tubulin

Purification

Protein A affinity purified from an animal origin-free culture supernatant

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser- 16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear (By similarity) .

Molecular Weight

17303 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Stathmin

Subcellular Location

Cytoplasm, cytoskeleton.