Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 — image 1 of 2

Product details

Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287

Catalog number M01975-1

Price for M01975-1

Size / count 100 µL

About this product

Boster Bio Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 (Catalog # M01975-1) . Tested in IHC, WB applications. This antibody reacts with Human.

Specifications

Catalog number: M01975-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
Synonyms: Alpha-actinin-4 ; Non-muscle alpha-actinin 4 ; ACTN4
Gene Name: ACTN4
UniProt: O43707
Host: Rabbit
Reactivity: Human
Cross Reactivity: This antibody reacts to human alpha-Actinin-4.
Immunogen: A peptide corresponding to the N-terminus of human alpha-Actinin-4
Clonality: Monoclonal
Clone: Clone: RM287
Tissue Specificity: Widely expressed.
Applications: IHC, WB
Field of Research: Invasion/Microenvironment, Metabolism, Metabolism Processes, Microfilaments, Pathways and Processes, Response To Hypoxia, Signal Transduction
Purification: Protein A affinity purified from an animal origin-free culture supernatant
Concentration: 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Form: Liquid
Function: F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (Probable) . Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (PubMed:15772161) . Involved in tight junction assembly in epithelial cells probably through interaction with MICALL2. Links MICALL2 to the actin cytoskeleton and recruits it to the tight junctions (By similarity) . May also function as a transcriptional coactivator, stimulating transcription mediated by the nuclear hormone receptors PPARG and RARA (PubMed:22351778) .
Molecular Weight: 104854 MW
Shipping Conditions: Available
Storage Conditions: Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment: Rabbit IgG
Other Gene Names: Alpha-actinin-4
Subcellular Location: Nucleus. Cytoplasm. Cell junction. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Colocalizes with actin stress fibers. Nuclear translocation can be induced by the PI3 kinase inhibitor wortmannin or by cytochalasin D. Exclusively localized in the nucleus in a limited number of cell lines (breast cancer cell line MCF-7, oral floor cancer IMC- 2, and bladder cancer KU-7) .

Frequently Asked Questions

What is the catalog number for Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287?

The catalog number for Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 is M01975-1.

What sizes are available for Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287?

Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 is available in the following size(s): 100 µL.

Is Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 in stock?

Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287?

The safety data sheet for Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 is available here: https://www.bosterbio.com/msds?sku=M01975-1.

What is Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 used for?

Boster Bio Anti-Alpha Actinin-4 ACTN4 Rabbit Monoclonal Antibody, Clone#RM287 (Catalog # M01975-1) . Tested in IHC, WB applications. This antibody reacts with Human.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.