Anti-AHA1 Monoclonal Antibody

About this product

Boster Bio Anti-AHA1 Monoclonal Antibody catalog # M05733-1. Tested in ELISA, IP, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Specifications

Catalog number

M05733-1

Size / count

100 µg

Dry ice

No

Hazardous

No

Discontinued

Yes

Background

Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2) . It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3) . Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4) .

Synonyms

Aha 1, Ahsa1, p38, HSPC322, C14orf3, Activator of HSP90 ATPase, Activator of 90 kDa heat shock protein ATPase homolog 1

Gene Name

AHA1

UniProt

Q8BK64

Host

Rat

Reactivity

Human, Mouse, Rat

Cross Reactivity

Detects ~38kDa. Can run up to 45kDa on SDS Page.

Immunogen

Recombinant Full Length Mouse Aha1 Protein

Clonality

Monoclonal

Clone

Clone: 25F2.D9

Applications

WB, IHC, ICC, IF, IP, ELISA

Field of Research

Chaperones, Golgi Proteins, Protein Trafficking, Signal Transduction

Purification

Protein G Purified

Concentration

1.2 mg/ml

Dilution

WB (1:1000), IHC (1:100), ICC/IF (1:1000), IP (1:1000) ; optimal dilutions for assays should be determined by the user.

Form

Liquid

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Fragment

IgG2a Kappa

Subcellular Location

Cytoplasm. Endoplasmic Reticulum

Protein Name

AHA1