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Product details

Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172

Catalog number M06819-13

Price for M06819-13

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Size / count 100 µg

About this product

Boster Bio Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 (Catalog # M06819-13) . Tested in WB, ICC, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates.

Specifications

Catalog number
M06819-13
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
Histone H3.3; H3F3A; H3.3A, H3F3; PP781; H3F3B; H3.3B
Gene Name
H3F3A
UniProt
P84243
Host
Rabbit
Reactivity
Human, Vertebrates
Cross Reactivity
This antibody reacts to Histone H3 acetylated at Lysine 27 (K27ac) . No cross-reactivity with other acetylated Lysines in histone H3.
Immunogen
An acetyl-peptide corresponding to the Acetyl-Histone H3 (Lys27)
Clonality
Monoclonal
Clone
Clone: RM172
Applications
WB, ICC, ELISA, Luminex
Field of Research
2339, Epigenetics and Nuclear Signaling, Histones
Purification
Protein A affinity purified from an animal origin-free culture supernatant
Concentration
1 mg/mL
Form
Liquid
Function
Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Molecular Weight
15328 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment
Rabbit IgG
Other Gene Names
Histone H3.3
Subcellular Location
Nucleus. Chromosome.

Frequently Asked Questions

What is the catalog number for Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172?

The catalog number for Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 is M06819-13.

What sizes are available for Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172?

Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 is available in the following size(s): 100 µg.

Is Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 in stock?

Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172?

The safety data sheet for Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 is available here: https://www.bosterbio.com/msds?sku=M06819-13.

What is Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 used for?

Boster Bio Anti-Acetyl-Histone H3 (Lys27) H3F3A Rabbit Monoclonal Antibody, Clone#RM172 (Catalog # M06819-13) . Tested in WB, ICC, ELISA, Luminex applications. This antibody reacts with Human, Vertebrates.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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