Anti-KDEL Receptor Monoclonal Antibody

Catalog number M07617-2

Discontinued

Price for M07617-2

Size / count 100 µg

This variant is discontinued and cannot be added to your cart.

About this product

Boster Bio Anti-KDEL Receptor Monoclonal Antibody catalog # M07617-2. Tested in IP, IF, IHC, ICC, WB applications. This antibody reacts with Bovine, Chicken, Dog, Fruit fly, Hamster, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Frog.

Specifications

Catalog number: M07617-2
Size / count: 100 µg
Dry ice: No
Hazardous: No
Discontinued: Yes
Background: The endoplasmic reticulum is part of a protein sorting pathway, or in essence, the transportation system of the eukaryotic cell. The majority of endoplasmic reticulum resident proteins are retained in the endoplasmic reticulum through a retention motif. This motif is composed of four amino acids at the C-terminal end of the protein sequence. The most common retention sequence is KDEL (lys-asp-glu-leu) . However, variation on KDEL does occur and other sequences can also give rise to endoplasmic reticulum retention (6) . There are three KDEL receptors in mammalian cells, all have a very high degree of sequence identity; and all are located within the cis-Golgi and its intermediate compartments (4) . In terms of function, KDEL receptors interact with GAP (GTPase-activating protein) of ARF1, which is involved in COPI dependent vesicle transport, and the KDEL receptor may also be responsible for the recruitment of this ARF1 to membranes which can then aid in the regulation of vesicle budding (3) . It is also important to note that the KDEL receptor exhibits extensive sequence identity o yeast protein Erd2p, which is a receptor for the yeast ER retention signal (4, 5) .
Synonyms: ERD2, ERD2.1, ERD21, HDEL, KDEL, KDEL R1, KDELR1, PM23
Gene Name: KDELR1
UniProt: P33946
Host: Mouse
Reactivity: Human, Mouse, Rat, Bovine, Monkey, Hamster, Rabbit, Pig, Sheep, Dog, Chicken, Drosophila, Xenopus
Cross Reactivity: Detects ~25kDa.
Immunogen: A 21 residue synthetic peptide (amino acids 192-212) based on the bovine KDEL receptor and the peptide coupled to KLH
Clonality: Monoclonal
Clone: Clone: KR-10
Applications: WB, IHC, ICC, IF, IP
Field of Research: ER Proteins, Organelles, Protein Trafficking, Signal Transduction, Subcellular Markers, Tags & Cell Markers
Purification: Protein G Purified
Concentration: 1 mg/ml
Dilution: WB (1:1000), ICC/IF (1:1000) ; optimal dilutions for assays should be determined by the user.
Form: Liquid
Shipping Conditions: Available
Storage Conditions: Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Fragment: IgG1
Subcellular Location: Endoplasmic Reticulum
Protein Name: KDEL Receptor

Frequently Asked Questions

What is the catalog number for Anti-KDEL Receptor Monoclonal Antibody?

The catalog number for Anti-KDEL Receptor Monoclonal Antibody is M07617-2.

Is Anti-KDEL Receptor Monoclonal Antibody in stock?

Anti-KDEL Receptor Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-KDEL Receptor Monoclonal Antibody?

The safety data sheet for Anti-KDEL Receptor Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M07617-2.

What is Anti-KDEL Receptor Monoclonal Antibody used for?

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.