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Product details

Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody

Catalog number M30942

Discontinued

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Size / count 100 µg

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About this product

Boster Bio Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody (Catalog # M30942) . Tested in IHC applications. This antibody reacts with Human.

Specifications

Catalog number
M30942
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
Yes
Background
This monoclonal antibody reacts with a protein of ~13kDa, identified as alpha sub-unit of Luteinizing Hormone (LH) . Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG) . The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Synonyms
Glycoprotein hormones alpha chain; Anterior pituitary glycoprotein hormones common subunit alpha; Choriogonadotropin alpha chain; Chorionic gonadotrophin subunit alpha; CG-alpha; Follicle-stimulating hormone alpha chain; FSH-alpha; Follitropin alpha chain; Luteinizing hormone alpha chain; LSH-alpha; Lutropin alpha chain; Thyroid-stimulating hormone alpha chain; TSH-alpha; Thyrotropin alpha chain; CGA
Gene Name
LHA
UniProt
P01215
Host
Mouse
Reactivity
Human
Immunogen
Recombinant full-length hLH alpha protein
Clonality
Monoclonal
Clone
Clone: Clone: LHa/756
Applications
IHC
Field of Research
Cancer, Cell Type Marker, Cell Type Markers, Growth Factors, Growth Factors/Hormones, Neuron Marker, Neuroscience, Signal Transduction, Tags & Cell Markers, Tumor Associated, Tumor Biomarkers
Purification
200ug/ml of antibody purified from Bioreactor Concentrate by Protein A/G.
Concentration
Purified antibody with BSA and azide at 200ug/ml
Dilution
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (No special pre-treatment is required for staining of formalin-fixed tissues. Note that HIER is NOT recommended for this antibody.) Optimal dilution for a specific application should be determined.
Form
Liquid
Molecular Weight
13075 MW
Shipping Conditions
Available
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Fragment
IgG1, kappa
Other Gene Names
Glycoprotein hormones alpha chain
Subcellular Location
Cytoplasmic and Secreted

Frequently Asked Questions

What is the catalog number for Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody?

The catalog number for Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody is M30942.

Is Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody in stock?

Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody?

The safety data sheet for Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody is available here: https://www.bosterbio.com/msds?sku=M30942.

What is Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody used for?

Boster Bio Anti-LH, alpha (Luteinizing Hormone, alpha) CGA Monoclonal Antibody (Catalog # M30942) . Tested in IHC applications. This antibody reacts with Human.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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