Mouse IL-1 beta Recombinant Protein

About this product

IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE) . This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Mouse IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Specifications

Catalog number

R00101-7

Size / count

5 µg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Interleukin-1 beta; IL-1 beta; Il1b

Gene Name

IL1B

UniProt

P10749

Tissue Specificity

Expressed in activated macrophages (at protein level) .

Source

Yeast

Sequence

[object Object]

Applications

Cell Culture

Field of Research

Atherosclerosis, Cardiovascular, Cytokines, Immunology, Innate Immunity, Interleukins, Metabolism, Obesity, Vascular Inflammation

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Subcellular Location

Cytoplasm, cytosol.