Mouse CCL3 Recombinant Protein

About this product

Chemokine ligand 3 (CCL3), also known as Macrophage inflammatory protein-1 alpha (MIP-1 alpha) is a small cytokine belonging to the CC chemokine family. CCL3/MIP-1 alpha is a chemoattractant for several different leukocytes, with varying degrees of potency (monocytes = T-cells>neutrophils>eosinophils) .

Specifications

Catalog number

R00405-2

Size / count

5 µg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

C-C motif chemokine 3; Heparin-binding chemotaxis protein; L2G25B; Macrophage inflammatory protein 1-alpha; MIP-1-alpha; SIS-alpha; Small-inducible cytokine A3; TY-5; Ccl3; Mip1a; Scya3

Gene Name

CCL3

UniProt

P10855

Tissue Specificity

Expressed in lung, spleen, and pancreas.

Source

Yeast

Sequence

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Applications

Cell Culture

Field of Research

Antiviral Signaling, Chemokines, Immune System Diseases, Immunology, Innate Immunity, Macrophage/Inflammation

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Subcellular Location

Secreted.