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Product details

Human CCL4 Recombinant Protein

Catalog number R00703-3

Price for R00703-3

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Size / count 5 µg

About this product

The small chemotactic cytokine CCL4 (MIP-1 beta) is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is involved in several inflammatory and autoimmune diseases including viral infection such as HIV-1/AIDS. Human CCL4 Recombinant Protein is purified chemokine ligand 4 (CCL4, MIP-1 beta) produced in yeast.

Specifications

Catalog number
R00703-3
Size / count
5 µg
Dry ice
No
Hazardous
No
Discontinued
No
Synonyms
C-C motif chemokine 4; G-26 T-lymphocyte-secreted protein; HC21; Lymphocyte activation gene 1 protein; LAG-1; MIP-1-beta (1-69) ; Macrophage inflammatory protein 1-beta; MIP-1-beta; PAT 744; Protein H400; SIS-gamma; Small-inducible cytokine A4; T-cell activation protein 2; ACT-2; MIP-1-beta (3-69) ; CCL4; LAG1, MIP1B; SCYA4
Gene Name
CCL4
UniProt
P13236
Source
Yeast
Sequence
[object Object]
Applications
Cell Culture
Field of Research
Antiviral Signaling, Chemokines, Immune System Diseases, Immunology, Innate Immunity, Macrophage/Inflammation
Purification
Ion-exchange chromatography.
Bioactivity
In testing.
Form
Lyophilized
Function
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) . The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B.
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Subcellular Location
Secreted.

Frequently Asked Questions

What is the catalog number for Human CCL4 Recombinant Protein?

The catalog number for Human CCL4 Recombinant Protein is R00703-3.

What sizes are available for Human CCL4 Recombinant Protein?

Human CCL4 Recombinant Protein is available in the following size(s): 5 µg.

Is Human CCL4 Recombinant Protein in stock?

Human CCL4 Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Human CCL4 Recombinant Protein?

The safety data sheet for Human CCL4 Recombinant Protein is available here: https://www.bosterbio.com/msds?sku=R00703-3.

What is Human CCL4 Recombinant Protein used for?

The small chemotactic cytokine CCL4 (MIP-1 beta) is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is involved in several inflammatory and autoimmune diseases including viral infection such as HIV-1/AIDS. Human CCL4 Recombinant Protein is purified che

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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