Mouse IL-1 alpha Recombinant Protein

About this product

IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Mouse IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

Specifications

Catalog number

R01144-5

Size / count

5 µg

Dry ice

No

Hazardous

No

Discontinued

No

Synonyms

Interleukin-1 alpha; IL-1 alpha; Il1a

Gene Name

IL1A

UniProt

P01582

Source

Yeast

Sequence

[object Object]

Applications

Cell Culture

Field of Research

Cancer, Cytokines, Immunology, Innate Immunity, Interleukins, Tumor Immunology

Purification

Ion-exchange chromatography.

Bioactivity

In testing.

Form

Lyophilized

Function

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. Avoid repeated freeze-thaw cycles.

Subcellular Location

Secreted. The lack of a specific hydrophobic segment in the precursor sequence suggests that IL-1 is released by damaged cells or is secreted by a mechanism differing from that used for other secretory proteins.