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Product details

LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43]

Catalog number HA722143

Price for HA722143

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Size / count 100 µL

About this product

Platelet-activating factor acetylhydrolase IB subunit alpha is an enzyme that in humans is encoded by the PAFAH1B1 gene. The protein is often referred to as Lis1 and plays an important role in regulating the motor protein Dynein. PAFAH1B1 was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller–Dieker syndrome. PAFAH1B1 encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acetylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum.

Specifications

Catalog number
HA722143
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
LIS 1 antibody LIS 2 antibody LIS-1 antibody LIS1 antibody LIS1_HUMAN antibody LIS2 antibody Lissencephaly 1 protein antibody Lissencephaly-1 protein antibody MDCR antibody MDS antibody PAF acetylhydrolase 45 kDa subunit antibody PAF AH 45 kDa subunit antibody PAF AH alpha antibody PAF-AH 45 kDa subunit antibody PAF-AH alpha antibody PAFAH alpha antibody PAFAH antibody PAFAH1B1 antibody PAFAHA antibody Platelet activating factor acetylhydrolase 1b regulatory subunit 1 antibody Platelet activating factor acetylhydrolase isoform Ib alpha subunit antibody Platelet-activating factor acetylhydrolase IB subunit alpha antibody
Abbreviation
PAFAH1B1, LIS1, MDCR, MDS, PAFAHA
Swiss Prot
P43034 Human, P63005 Mouse, P63004 Rat
Cellular Locus
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, spindle, Nucleus membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Synthetic peptide within Human LIS1 aa 51-100 / 410.
Isotype
IgG
Clone
JE37-43
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
HeLa cell lysate, 293T cell lysate, C2C12 cell lysate, C6 cell lysate, COS-1 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43]?

The catalog number for LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43] is HA722143.

What sizes are available for LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43]?

LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43] is available in the following size(s): 100 µL.

Is LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43] in stock?

LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LIS1 Recombinant Rabbit Monoclonal Antibody [JE37-43] used for?

Platelet-activating factor acetylhydrolase IB subunit alpha is an enzyme that in humans is encoded by the PAFAH1B1 gene. The protein is often referred to as Lis1 and plays an important role in regulating the motor protein Dynein. PAFAH1B1 was identified as encoding a gene that when mutated or lost c

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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