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Product details

ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80]

Catalog number HA722479

Price for HA722479

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Size / count 100 µL

About this product

Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER. Overexpression as well as silencing of ZW10 disrupts the morphology of the ER-Golgi intermediate compartment as well as the Golgi apparatus and slows down ER-Golgi transport.

Specifications

Catalog number
HA722479
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Centromere/kinetochore protein zw10 antibody Centromere/kinetochore protein zw10 homolog antibody HZW 10 antibody HZW10 antibody Kinetochore associated homolog antibody KNTC1AP antibody MGC149821 antibody Zeste white 10 antibody Zeste white 10 homolog antibody ZW 10 antibody ZW 10 homolog centromere/kinetochore protein antibody ZW 10 kinetochore associated homolog antibody ZW10 (Drosophila) homolog centromere/kinetochore protein antibody Zw10 antibody ZW10 homolog centromere/kinetochore protein (Drosophila) antibody ZW10 homolog centromere/kinetochore protein antibody ZW10 kinetochore associated homolog antibody ZW10, kinetochore associated, homolog (Drosophila) antibody ZW10_HUMAN antibody
Abbreviation
Centromere/kinetochore protein zw10 homolog ZW10
Swiss Prot
O43264 Human, O54692 Mouse, Q4V8C2 Rat
Cellular Locus
Centromere, Chromosome, Cytoplasm, Cytoskeleton, Endoplasmic reticulum.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Monkey
Immunogen
Recombinant protein within Human ZW10 aa 350-779.
Isotype
IgG
Clone
PSH05-80
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Jurkat cell lysate, K-562 cell lysate, Ramos cell lysate, U-2 OS cell lysate, HCT 116 cell lysate, SW620 cell lysate, HeLa cell lysate, COS-1 cell lysate, NIH/3T3 cell lysate, C6 cell lysate, PC-12 cell lysate, human testis tissue, mouse testis tissue, rat testis tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IHC-P: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 89 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80]?

The catalog number for ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80] is HA722479.

What sizes are available for ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80]?

ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80] is available in the following size(s): 100 µL.

Is ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80] in stock?

ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ZW10 Recombinant Rabbit Monoclonal Antibody [PSH05-80] used for?

Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mit

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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